DHEA is mostly produced in the adrenal glands however a small amount is produced in the ovaries. Most of the DHEA in your body exists in your blood in the sulphated form, DHEA-S, which we measure in this test. DHEA is important in the production of sex hormones, testosterone and estrogen. DHEA boosts the immune system and protects blood vessels against atherosclerosis. DHEA levels in the body naturally decline as you get older. Low level of DHEA-S may be linked to diabetes, osteoporosis, dementia, cardiovascular disease, depression, thinning and dryness of the vaginal tissue, low sex-drive.